General Information:

Id: 864 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Homo sapiens
article
Reference: Ansar S et al.(2007) A non-toxic Hsp90 inhibitor protects neurons from Abeta-induced toxicity. Bioorg. Med. Chem. Lett. 17: 1984-1990 [PMID: 17276679]

Interaction Information:

Comment A non-toxic C-terminal Hsp90 inhibitor, A4 (a novobiocin analogue), protects neurons from Abeta-induced toxicity.
Formal Description
Interaction-ID: 5123

drug/chemical compound

A4 (novobiocin analogue)

decreases_activity of

gene/protein

Amyloid beta peptide

in neurons