General Information:

Id: 855 (click here to show other Interactions for entry)
Diseases: Breast cancer - [OMIM]
Parkinson disease
Mus musculus
Reference: Kim RH et al.(2005) DJ-1, a novel regulator of the tumor suppressor PTEN. Cancer Cell 7: 263-273 [PMID: 15766664]

Interaction Information:

Comment DJ-1 plays a role in the pathogenesis of primary breast cancer. DJ-1 may modulate PTEN function such that PKB/Akt becomes hyperphosphorylated and promotes abnormal cell survival.
Formal Description
Interaction-ID: 5098



increases_activity of


Breast cancer

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