General Information:

Id: 835 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Neurological
Mus musculus
IRE1 -/- mouse
BTO:0001078 placenta
article
Reference: Iwawaki T et al.(2009) Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability. Proc. Natl. Acad. Sci. U.S.A. 106 [PMID: 19805353]

Interaction Information:

Comment Apoptosis level in the IRE1alpha-deficient placenta was very low and was similar to that in the wild-type placenta, although severe ER stress is known to induce apoptosis, and IRE1alpha is believed to be necessary for mitigating ER stress.
Formal Description
Interaction-ID: 4981

gene/protein

ERN1

NOT affects_activity of

process

apoptotic process

in IRE1alpha-deficient placenta.
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