General Information:
Id: | 835 (click here to show other Interactions for entry) |
Diseases: |
Amyotrophic lateral sclerosis
Neurological |
Mus musculus | |
IRE1 -/- mouse | |
BTO:0001078 placenta | |
article | |
Reference: | Iwawaki T et al.(2009) Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability Proc. Natl. Acad. Sci. U.S.A. 106 [PMID: 19805353] |
Interaction Information:
Comment | Apoptosis level in the IRE1alpha-deficient placenta was very low and was similar to that in the wild-type placenta, although severe ER stress is known to induce apoptosis, and IRE1alpha is believed to be necessary for mitigating ER stress. |
Formal Description Interaction-ID: 4981 |
gene/protein NOT affects_activity of process |
Drugbank entries | Show/Hide entries for ERN1 |