General Information:

Id: 832 (click here to show other Interactions for entry)
Diseases: Neurological
Schizophrenia - [OMIM]
Mammalia
review
Reference: Hudmon A and Schulman H(2002) Structure-function of the multifunctional Ca2+/calmodulin-dependent protein kinase II Biochem. J. 364: 593-611 [PMID: 11931644]

Interaction Information:

Comment Ca(2+)/calmodulin (CaM) binding activates CaMKII kinase and disinhibits its autoregulatory domain, allowing autophosphorylation.
Formal Description
Interaction-ID: 59106

drug/chemical compound

Ca2+

increases_activity of

complex/PPI

Calcium/calmodulin-dependent protein kinase type II