General Information:

Id: 824 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Mammalia
review
Reference: Sugden MC et al.(2010) PPAR control: its SIRTainly as easy as PGC J. Endocrinol. 2: 93-104 [PMID: 19770177]

Interaction Information:

Comment In mature adipocytes, SIRT1 binds and represses PPAR-gamma in association with mobilization of fat stores during food deprivation.
Formal Description
Interaction-ID: 5080

gene/protein

SIRT1

increases_activity of

process

fat reserve metabolic process

in adipose tissue, in mature adipocytes; during food deprivation