General Information:

Id: 824 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Mammalia
review
Reference: Sugden MC et al.(2010) PPAR control: its SIRTainly as easy as PGC J. Endocrinol. 2: 93-104 [PMID: 19770177]

Interaction Information:

Comment Lipin-1 induces PPAR-alpha gene expression as well as forming an interactive complex with PPAR-alpha and PGC-1alpha leading to induction of FA oxidation genes including CPT1.
Formal Description
Interaction-ID: 4894

gene/protein

LPIN1

increases_expression of

gene/protein

PPARA

in nucleus
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