General Information:
Id: | 824 (click here to show other Interactions for entry) |
Diseases: |
Diabetes mellitus, type II
- [OMIM]
Insulin resistance Obesity - [OMIM] |
Mammalia | |
review | |
Reference: | Sugden MC et al.(2010) PPAR control: its SIRTainly as easy as PGC J. Endocrinol. 2: 93-104 [PMID: 19770177] |
Interaction Information:
Comment | PGC-1alpha subsequently coactivates and forms complexes with FoxO1, the GR and HNF-4alpha, which (as well as PPAR-alpha) are essential for expression of the key gluconeogenic genes PCK1 and/or G6Pase. |
Formal Description Interaction-ID: 4858 |
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