General Information:

Id: 824 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Mammalia
review
Reference: Sugden MC et al.(2010) PPAR control: its SIRTainly as easy as PGC J. Endocrinol. 2: 93-104 [PMID: 19770177]

Interaction Information:

Comment PGC-1alpha subsequently coactivates and forms complexes with FoxO1, the GR and HNF-4alpha, which (as well as PPAR-alpha) are essential for expression of the key gluconeogenic genes PCK1 and/or G6Pase.
Formal Description
Interaction-ID: 4855

gene/protein

PPARGC1A

increases_activity of

gene/protein

HNF4A

in liver
Drugbank entries Show/Hide entries for HNF4A