General Information:

Id: 824 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Mammalia
review
Reference: Sugden MC et al.(2010) PPAR control: its SIRTainly as easy as PGC J. Endocrinol. 2: 93-104 [PMID: 19770177]

Interaction Information:

Comment SIRT1, located in the cell nucleus, requires NAD(+) as a cofactor and is negatively regulated by either NADH or the deacetylation product nicotinamide.
Formal Description
Interaction-ID: 4818

gene/protein

SIRT1

is localized in

cellular component

nucleus