General Information:

Id: 824 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Mammalia
review
Reference: Sugden MC et al.(2010) PPAR control: its SIRTainly as easy as PGC J. Endocrinol. 2: 93-104 [PMID: 19770177]

Interaction Information:

Comment The PGC-1s are a small family of transcriptional coactivators that play a critical role in the control of glucose, lipid, and energy metabolism. There are three known isoforms of PGC-1: PGC-1alpha (PPARGC1A); PGC-1beta (PPARGC1B); PGC-1-related coactivator (PRC or PPRC1).
Formal Description
Interaction-ID: 4805

gene/protein

PPARGC1A

affects_activity of

via regulation of a transcription factor