General Information:

Id: 824 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Mammalia
review
Reference: Sugden MC et al.(2010) PPAR control: its SIRTainly as easy as PGC J. Endocrinol. 2: 93-104 [PMID: 19770177]

Interaction Information:

Comment In skeletal muscle, phosphorylation by AMPK and p38 MAPK increases stabilization of PGC-1alpha.
Formal Description
Interaction-ID: 4797

complex/PPI

AMPK

increases_quantity of

gene/protein

PPARGC1A

in skeletal muscle; via decreased degradation of PPARGC1A