General Information:

Id: 824 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Mammalia
review
Reference: Sugden MC et al.(2010) PPAR control: its SIRTainly as easy as PGC J. Endocrinol. 2: 93-104 [PMID: 19770177]

Interaction Information:

Comment Ligand binding to PPAR-alpha causes PPAR-alpha to heterodimerize with the RXR and recruit coactivators to activate a program of lipid-induced activation of genes encoding proteins involved in fatty acid uptake, activation, and oxidation.
Formal Description
Interaction-ID: 4766

gene/protein

PPARA

interacts (colocalizes) with

gene/protein

RXR

upon ligand binding
Drugbank entries Show/Hide entries for PPARA