Latreille M and Larose L(2006) Nck in a complex containing the catalytic subunit of protein phosphatase 1 regulates eukaryotic initiation factor 2alpha signaling and cell survival to endoplasmic reticulum stress. J. Biol. Chem. 281
The number of apoptotic cells was significantly reduced in mutant mouse embryonic fibroblasts as compared with wild-type cells in Er stress conditions, confirming that the MEFs lacking Nck are protected from ER stress-induced cell death.
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