General Information:

Id: 792 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Mammalia
review
Reference: Koren J 3rd et al.(2009) Chaperone signalling complexes in Alzheimers disease J. Cell. Mol. Med. 13: 619-630 [PMID: 19449461]

Interaction Information:

Comment PS1 forms aggresomes within the ER upon heat shock stress. The functional consequence of these aggresomes remains unclear.
Formal Description
Interaction-ID: 4682

gene/protein

PSEN1

increases_activity of

in endoplasmic reticulum; as response to heat shock stress (GO:0009408 )