General Information:

Id: 792 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Mammalia
review
Reference: Koren J 3rd et al.(2009) Chaperone signalling complexes in Alzheimers disease J. Cell. Mol. Med. 13: 619-630 [PMID: 19449461]

Interaction Information:

Comment The mutations in APOE linked to LOAD reduce the efficiency with which ApoE clears the Abeta peptide, facilitating amyloid accumulation and disease progression.
Formal Description
Interaction-ID: 4543

gene/protein mutant

APOE-mut

affects_quantity of

gene/protein

Amyloid beta peptide