General Information:

Id: 787 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Fatty liver disease, nonalcoholic
Insulin resistance
Mus musculus
article
Reference: Finck BN et al.(2006) Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway Cell Metab. 3: 199-210 [PMID: 16950137]

Interaction Information:

Comment Consistent with an activation of hepatic fatty acid oxidation, levels of plasma beta-hydroxybutyrate, a product of ketogenesis, were significantly elevated with lipin 1 overexpression.
Formal Description
Interaction-ID: 4471

gene/protein

LPIN1

increases_activity of

if LPIN1 is overexpressed