General Information:

Id: 785 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Homo sapiens
BTO:0000793 SH-SY5Y cell; BTO:0002104 BE(2)M17 cell
article
Reference: Lim MK et al.(2007) Parkin interacts with LIM Kinase 1 and reduces its cofilin-phosphorylation activity via ubiquitination Exp. Cell Res. 313: 2858-2874 [PMID: 17512523]

Interaction Information:

Comment Parkin reduces LIMK1-induced actin filament aggregation through interaction and ubiquitination of LIMK1.
Formal Description
Interaction-ID: 4446

gene/protein

PARK2

increases_activity of

through ubiquitination of LIMK1