General Information:

Id: 774 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Mus musculus
SOD1(-/-) mouse
BTO:0001103 skeletal muscle
Reference: Muller FL et al.(2007) Denervation-induced skeletal muscle atrophy is associated with increased mitochondrial ROS production. Am. J. Physiol. Regul. Integr. Comp. Physiol. 293 [PMID: 17584954]

Interaction Information:

Comment Skeletal muscle mitochondrial ROS production is increased in Sod1 null mice and is associated with the degree of muscle atrophy. By 20 mo of age, ROS production in mitochondria from Sod1(-/-) mice was threefold higher than in the age-matched wild-type mice.
Formal Description
Interaction-ID: 4363



decreases_quantity of

drug/chemical compound

Reactive oxygen species

in skeletal muscle mitochondria
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