General Information:

Id: 763
Diseases: Alzheimer disease - [OMIM]
Rattus norvegicus
male
brain
article
Reference: Cole AR et al.(2004) GSK-3 phosphorylation of the Alzheimer epitope within collapsin response mediator proteins regulates axon elongation in primary neurons. J. Biol. Chem. 279 [PMID: 15466863]

Interaction Information:

Comment GSK-3 phosphorylation of the Alzheimer epitope within collapsin response mediator proteins (CRMP2 and CRMP4) regulates axon elongation in primary neurons.
Formal Description
Interaction-ID: 4300

gene/protein

GSK3B

affects_phosphorylation of

gene/protein

DPYSL2

Drugbank entries Show/Hide entries for GSK3B
Comment GSK-3 phosphorylation of the Alzheimer epitope within collapsin response mediator proteins (CRMP2 and CRMP4) regulates axon elongation in primary neurons.
Formal Description
Interaction-ID: 4303

gene/protein

GSK3B

affects_phosphorylation of

gene/protein

DPYSL3

CRMP4 is phosphorlated at Thr509, Thr514, Ser518
Drugbank entries Show/Hide entries for GSK3B
Comment GSK-3 phosphorylation of the Alzheimer epitope within collapsin response mediator proteins (CRMP2 and CRMP4) regulates axon elongation in primary neurons.
Formal Description
Interaction-ID: 4304

gene/protein

GSK3B

affects_activity of

gene/protein

DPYSL2

Drugbank entries Show/Hide entries for GSK3B
Comment GSK-3 phosphorylation of the Alzheimer epitope within collapsin response mediator proteins (CRMP2 and CRMP4) regulates axon elongation in primary neurons.
Formal Description
Interaction-ID: 4305

gene/protein

GSK3B

affects_activity of

gene/protein

DPYSL3

Drugbank entries Show/Hide entries for GSK3B
Comment GSK-3 phosphorylation of the Alzheimer epitope within collapsin response mediator proteins (CRMP2 and CRMP4) regulates axon elongation in primary neurons.
Formal Description
Interaction-ID: 4320

protein modification

DPYSL2-p

affects_activity of

process

axonogenesis

in primary neurons; phosphorylated DPYSL2/CRMP2