General Information:

Id: 71 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type I - [OMIM]
Rattus norvegicus
BTO:0001185 RINm5F cell
article
Reference: Kim EK et al.(2007) Activation of peroxisome proliferator-activated receptor-gamma protects pancreatic beta-cells from cytokine-induced cytotoxicity via NF kappaB pathway. Int. J. Biochem. Cell Biol. 39: 1260-1275 [PMID: 17521952]

Interaction Information:

Comment The thiazolidinediones (high affinity ligands for PPAR-gamma) CGZ and TGZ prevented the cytokine-mediated decrease in cell proliferation potential.
Formal Description
Interaction-ID: 219

drug/chemical compound

Ciglitazone

increases_activity of

in cytokine treated cells