General Information:

Id: 719 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Rattus norvegicus
article
Reference: Feyt C et al.(2005) Lithium chloride increases the production of amyloid-beta peptide independently from its inhibition of glycogen synthase kinase 3. J. Biol. Chem. 280 [PMID: 16014628]

Interaction Information:

Comment Inhibition of GSK3 by LiCl induced the nuclear translocation of beta-catenin in rat cultured neurons, in which a decrease in tau phosphorylation was observed.
Formal Description
Interaction-ID: 4048

drug/chemical compound

LiCl

decreases_activity of

gene/protein

GSK3B

Drugbank entries Show/Hide entries for GSK3B