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Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
Other
Parkinson disease
Post-traumatic stress disorder
Postpartum depression
Rare disease
Schizophrenia

	Field	Term

General Information:

Id:	7,172 (click here to show other Interactions for entry)
Diseases:	Acrocallosal syndrome - [OMIM] Joubert syndrome Short-rib thoracic dysplasia 3 with or without polydactyly - [OMIM]
Organism:	Mammalia
Publication type:	review
Reference:	[PMID: 27765513]

Interaction Information:

Comment	In all mouse Dync2h1 alleles analyzed, Shh signaling is reduced in the neural tube and mutants lack the floor plate and V3 progenitors, which are specified by the highest level of Shh activity.
Formal Description Interaction-ID: 70631	gene/protein DYNC2H1 affects_activity of process smoothened signaling pathway

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