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Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
Other
Parkinson disease
Post-traumatic stress disorder
Postpartum depression
Rare disease
Schizophrenia

	Field	Term

General Information:

Id:	7,172 (click here to show other Interactions for entry)
Diseases:	Acrocallosal syndrome - [OMIM] Joubert syndrome Short-rib thoracic dysplasia 3 with or without polydactyly - [OMIM]
Organism:	Mammalia
Publication type:	review
Reference:	[PMID: 27765513]

Interaction Information:

Comment	The mammalian Hedgehog (Hh) signaling pathway is required for development and for maintenance of adult stem cells, and overactivation of the pathway can cause tumorigenesis.
Formal Description Interaction-ID: 70596	process smoothened signaling pathway affects_activity of phenotype neoplasm

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