General Information:

Id: 715 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Mus musculus
parkin -/- mouse
article
Reference: Rawal N et al.(2009) Parkin protects dopaminergic neurons from excessive Wnt/beta-catenin signaling. Biochem. Biophys. Res. Commun. 388: 473-478 [PMID: 19591802]

Interaction Information:

Comment Beta-catenin mRNA levels were not significantly altered in parkin null ventral midbrain, indicating that accumulation of beta-catenin is possibly due to impaired degradation of beta-catenin protein.
Formal Description
Interaction-ID: 3979

gene/protein

PARK2

NOT affects_expression of

gene/protein

CTNNB1

in ventral midbrain dopaminergic neurons
Drugbank entries Show/Hide entries for CTNNB1