General Information:

Id: 710 (click here to show other Interactions for entry)
Diseases: Parkinson disease
Mammalia
BTO:0003945 MN9D cell; BTO:0000298 COS-7 cell
article
Reference: Rawal N et al.(2009) Parkin protects dopaminergic neurons from excessive Wnt/beta-catenin signaling Biochem. Biophys. Res. Commun. 388: 473-478 [PMID: 19591802]

Interaction Information:

Comment Overexpression of parkin in COS7 cells causes a reduction in the level of endogenous beta-catenin. The second RING domain of Parkin might be important for the regulation of beta-catenin protein levels.
Formal Description
Interaction-ID: 3974

gene/protein

PARK2

decreases_quantity of

gene/protein

CTNNB1

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