General Information:

Id: 706
Diseases: Alzheimer disease - [OMIM]
Mus musculus
Tg2576 mouse model
BTO:0000142 brain
article
Reference: Crouch PJ et al.(2005) Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42 J. Neurosci. 25: 672-679 [PMID: 15659604]

Interaction Information:

Comment Analysis of brain and liver from an Alzheimer's model mouse (Tg2576) revealed abundant amyloid beta peptide (Abeta) immunoreactivity within the brain mitochondria fraction.
Formal Description
Interaction-ID: 3878

gene/protein

Amyloid beta peptide

is localized in

tissue/cell line

brain

in mitochondria
Comment Analysis of brain and liver from an Alzheimer's model mouse (Tg2576) revealed abundant amyloid beta peptide (Abeta) immunoreactivity within the brain mitochondria fraction.
Formal Description
Interaction-ID: 3897

gene/protein

Amyloid beta peptide

is localized in

cellular component

mitochondrion

in brain