General Information:

Id: 703 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mammalia
review
Reference: Adeli K et al.(2001) Mechanisms of hepatic very low-density lipoprotein overproduction in insulin resistance. Trends Cardiovasc. Med. 11: 170-176 [PMID: 11597827]

Interaction Information:

Comment Statin (atorvastatin) treatment was found to partially reverse the hepatic VLDL-apoB overproduction in insulin-resistant Syrian golden hamsters.
Formal Description
Interaction-ID: 3948

drug/chemical compound

Atorvastatin

decreases_activity of

process

VLDL secretion

in insulin-resistant Syrian golden hamsters
Drugbank entries Show/Hide entries for Atorvastatin
Comment Atorvastatin treatment partially reversed the elevated hepatic level of MTP induced by fructose feeding and improved insulin sensitivity of hamster hepatocytes based on assessment of the phosphorylation status of the insulin receptor.
Formal Description
Interaction-ID: 3949

drug/chemical compound

Atorvastatin

increases_activity of

Drugbank entries Show/Hide entries for Atorvastatin