General Information:

Id: 694 (click here to show other Interactions for entry)
Diseases: Amyotrophic lateral sclerosis
Mus musculus
Nck1alpha -/- mouse
BTO:0000452 fibroblast
Reference: Nguyen DT et al.(2004) Nck-dependent activation of extracellular signal-regulated kinase-1 and regulation of cell survival during endoplasmic reticulum stress. Mol. Biol. Cell 15: 4248-4260 [PMID: 15201339]

Interaction Information:

Comment A 10-min treatment with Tunicamycin triggered mostly the activation of JNK-1 and p38MAPK in both FR3T3 (rat fibroblast) cells and IRE1alpha +/+ mouse embryonic fibroblasts (MEFs), whereas this activation was significantly lower in IRE1alpha -/- MEFs.
Formal Description
Interaction-ID: 3799



increases_activity of

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