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Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
Other
Parkinson disease
Post-traumatic stress disorder
Postpartum depression
Rare disease
Schizophrenia

	Field	Term

General Information:

Id:	692 (click here to show other Interactions for entry)
Diseases:	Amyotrophic lateral sclerosis
Organism:	Rattus norvegicus
Tissue/Cell line:	BTO:0000452 fibroblast
Publication type:	article
Reference:	Nguyen DT et al.(2004) Nck-dependent activation of extracellular signal-regulated kinase-1 and regulation of cell survival during endoplasmic reticulum stress Mol. Biol. Cell 15: 4248-4260 [PMID: 15201339]

Interaction Information:

Comment	Both the affinity and the binding capacity of ER membranes for Nck1 were reduced upon Azc treatment, suggesting a dissociation of ER-membrane bound Nck1 during stress.
Formal Description Interaction-ID: 3814	process response to endoplasmic reticulum stress increases_dissociation of gene/protein ERN1 from the ER membrane
Drugbank entries	Show/Hide entries for ERN1
Drugbank DB07382	N~2~-1H-benzimidazol-5-yl-N~4~-(3-cyclop ... not specified ERN1

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