General Information:

Id: 6,900 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mammalia
review
Reference: Maiese K(2016) Novel nervous and multi-system regenerative therapeutic strategies for diabetes mellitus with mTOR Neural Regen Res 3: 372-385 [PMID: 27127460]

Interaction Information:

Comment Activation of mTOR signaling with p70S6K can phosphorylate IRS-1 in the renin-angiotensin-aldosterone system during consumption of high fat diets that results in high circulating angiotensin II (ANG II) and insulin resistance.
Formal Description
Interaction-ID: 68067

gene/protein

MTOR

increases_quantity of

gene/protein

Angiotensin II

Drugbank entries Show/Hide entries for MTOR