General Information:

Id: 6,845 (click here to show other Interactions for entry)
Diseases: Inflammatory bowel disease
Homo sapiens
896 CD cases and 3204 healthy controls all of Caucasian origin
article
Reference: McGovern DP et al.(2010) Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohns disease Hum. Mol. Genet. 19: 3468-3476 [PMID: 20570966]

Interaction Information:

Comment GWAS in 896 Crohn disease cases and 3204 healthy controls identified associations with genes involved in tight junctions/epithelial integrity (ASHL, ARPC1A), innate immunity (EXOC2), dendritic cell biology (CADM1), macrophage development (MMD2), TGF-beta signaling (MAP3K7IP1) and FUT2 , a gene involved in the gastrointestinal mucosal expression of blood group A and B antigens.
Formal Description
Interaction-ID: 66622

gene/protein

TAB1

increases_activity of