General Information:

Id: 6,731 (click here to show other Interactions for entry)
Diseases: Cancer
Lung cancer - [OMIM]
Homo sapiens
article
Reference: Wu YY et al.(2011) SCUBE3 is an endogenous TGF-beta receptor ligand and regulates the epithelial-mesenchymal transition in lung cancer Oncogene 30: 3682-3693 [PMID: 21441952]

Interaction Information:

Comment The CUB domain of SCUBE3 interacted with the with the extracellular region of TGFbetaR-II indicating that SCUBE3 is a ligand of TGFbetaR-II and is therefore involved in TGF-beta signaling.
Formal Description
Interaction-ID: 65173

gene/protein

TGFBR2

increases_activity of

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