General Information:
Id: | 6,731 (click here to show other Interactions for entry) |
Diseases: |
Cancer
Lung cancer - [OMIM] |
Homo sapiens | |
article | |
Reference: | Wu YY et al.(2011) SCUBE3 is an endogenous TGF-beta receptor ligand and regulates the epithelial-mesenchymal transition in lung cancer Oncogene 30: 3682-3693 [PMID: 21441952] |
Interaction Information:
Comment | The CUB domain of SCUBE3 interacted with the with the extracellular region of TGFbetaR-II indicating that SCUBE3 is a ligand of TGFbetaR-II and is therefore involved in TGF-beta signaling. |
Formal Description Interaction-ID: 65173 |
gene/protein increases_activity of |
Drugbank entries | Show/Hide entries for TGFBR2 |