General Information:

Id: 6,731 (click here to show other Interactions for entry)
Diseases: Cancer
Lung cancer - [OMIM]
Homo sapiens
Reference: Wu YY et al.(2011) SCUBE3 is an endogenous TGF-beta receptor ligand and regulates the epithelial-mesenchymal transition in lung cancer Oncogene 30: 3682-3693 [PMID: 21441952]

Interaction Information:

Comment SCUBE3 induces SMAD2 phosphorylation indicating that SCUBE3 is able to induce the TGF-beta receptor signaling.
Formal Description
Interaction-ID: 65144



increases_activity of

in lung cancer cells H1299