General Information:

Id: 664 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type I - [OMIM]
Diabetes mellitus, type II - [OMIM]
Hypothyroidism
Insulin resistance
Mammalia
review
Reference: Coleman RA et al.(2000) Physiological and nutritional regulation of enzymes of triacylglycerol synthesis Annu. Rev. Nutr. 20: 77-103 [PMID: 10940327]

Interaction Information:

Comment In response to increases in the cellular AMP/ATP ratio, AMPK phosphorylates and inactivates liver acetyl-CoA carboxylase and decreases its product, malonyl-CoA, a potent inhibitor of CPT1 and beta-oxidation.
Formal Description
Interaction-ID: 3757

drug/chemical compound

Malonyl-CoA

decreases_activity of

in liver