General Information:

Id: 664 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type I - [OMIM]
Diabetes mellitus, type II - [OMIM]
Hypothyroidism
Insulin resistance
Mammalia
review
Reference: Coleman RA et al.(2000) Physiological and nutritional regulation of enzymes of triacylglycerol synthesis Annu. Rev. Nutr. 20: 77-103 [PMID: 10940327]

Interaction Information:

Comment In lean ZDF rats, adenovirus-mediated hyperleptinemia markedly decreases adipose tissue mRNA expression of acetyl-CoA carboxylase, fatty acid synthase, and mitochondrial GPAT.
Formal Description
Interaction-ID: 3704

gene/protein

LEP

affects_expression of

gene/protein

FASN

in adipose tissue; in lean ZDF rats
Drugbank entries Show/Hide entries for FASN