General Information:

Id: 654 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Fatty liver disease, nonalcoholic
Insulin resistance
Obesity - [OMIM]
Mammalia
review
Reference: Chen HC and Farese RV Jr(2005) Inhibition of triglyceride synthesis as a treatment strategy for obesity: lessons from DGAT1-deficient mice. Arterioscler. Thromb. Vasc. Biol. 25: 482-486 [PMID: 15569818]

Interaction Information:

Comment Insulin-stimulated glucose transport is increased in skeletal muscle and white adipose tissue of DGAT1-/- mice, and insulin-stimulated activities of phosphatidylinositol-3 kinase, protein kinase B, and protein kinase C-delta, three key molecules in the insulin signaling pathway, are also increased in the skeletal muscle of DGAT1-/- mice.
Formal Description
Interaction-ID: 3515

gene/protein

DGAT1

affects_activity of

in skeletal muscle; if stimulated by insulin