General Information:

Id: 6,487 (click here to show other Interactions for entry)
Diseases: Lung disease
Metabolic
Rattus norvegicus
cecal ligation and puncture (CLP)-induced tissue injury model
article/cited
Reference: Albayrak A et al.(2013) Protective effects of lithium: a new look at an old drug with potential antioxidative and anti-inflammatory effects in an animal model of sepsis Int. Immunopharmacol. 16: 35-40 [PMID: 23542012]

Interaction Information:

Comment Rats with CLP-induced tissue injury showed dense inflammatory cell infiltrations with a diffuse and nodular form. Total obstructions were seen in the pulmonary vessels. Administration of lithium results in a decrease of inflammatory cell infiltration.
Formal Description
Interaction-ID: 61563

drug/chemical compound

Lithium

decreases_activity of

in lung tissue of a CLP-induced lung injury model
Drugbank entries Show/Hide entries for Lithium