General Information:

Id: 6,487 (click here to show other Interactions for entry)
Diseases: Lung disease
Metabolic
Rattus norvegicus
cecal ligation and puncture (CLP)-induced tissue injury model
article/cited
Reference: Albayrak A et al.(2013) Protective effects of lithium: a new look at an old drug with potential antioxidative and anti-inflammatory effects in an animal model of sepsis Int. Immunopharmacol. 16: 35-40 [PMID: 23542012]

Interaction Information:

Comment The serum levels of the pro-inflammatory cytokines, TNF-alpha, IL-6, and IL-1beta decreased after administration of lithium in rats with CLP-induced lung injury.
Formal Description
Interaction-ID: 61559

drug/chemical compound

Lithium

decreases_quantity of

gene/protein

TNF

in serum; if expression has been upregulated in a CLP-induced lung injury model
Drugbank entries Show/Hide entries for Lithium or TNF