General Information:

Id: 645 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Homo sapiens
BTO:0000007 HEK-293 cells
Reference: Ryder J et al.(2003) Divergent roles of GSK3 and CDK5 in APP processing Biochem. Biophys. Res. Commun. 312: 922-929 [PMID: 14651959]

Interaction Information:

Comment Both, GSK3beta and CDK5, are involved in APP processing. The data implicate these two kinases in the pathogenesis of Alzheimer's disease but in a divergent manner.
Formal Description
Interaction-ID: 3446



affects_activity of

both, GSK3beta and CDK5, are involved in APP processing
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