General Information:

Id: 6,387 (click here to show other Interactions for entry)
Diseases: Metabolic
Mammalia
review
Reference: Cetrullo S et al.(2015) mTOR, AMPK, and Sirt1: Key Players in Metabolic Stress Management Crit. Rev. Eukaryot. Gene Expr. 25: 59-75 [PMID: 25955819]

Interaction Information:

Comment Several signals converge on Sirt1 to stimulate its protein deacetylase activity, which uses NAD+ as a cosubstrate and releases acetyl-ADP-ribose and nicotinamide (NAM).
Formal Description
Interaction-ID: 61632

gene/protein

SIRT1

increases_quantity of

drug/chemical compound

Nicotinamide

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