General Information:

Id: 637 (click here to show other Interactions for entry)
Diseases: Atherosclerosis
Diabetes mellitus, type II - [OMIM]
Insulin resistance
Niemann-Pick disease
Obesity - [OMIM]
Mammalia
article
Reference: Deevska GM et al.(2009) Acid Sphingomyelinase Deficiency Prevents Diet-induced Hepatic Triacylglycerol Accumulation and Hyperglycemia in Mice J. Biol. Chem. 284: 8359-8368 [PMID: 19074137]

Interaction Information:

Comment Acid sphingomyelinase activity plays an essential role in the regulation of glucose metabolism by regulating the hepatic accumulation of triacylglycerides and sphingolipids during consumption of a diet rich in saturated fats.
Formal Description
Interaction-ID: 3411

gene/protein

SMPD1

affects_activity of

in liver; after diet rich in saturated fats
Drugbank entries Show/Hide entries for SMPD1