General Information:

Id: 614 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Homo sapiens
article
Reference: Kang DE et al.(2002) Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis Cell 110: 751-762 [PMID: 12297048]

Interaction Information:

Comment PS1 acts as a negative regulator of the Wnt/beta-catenin signaling pathway.
Formal Description
Interaction-ID: 3248

gene/protein

PSEN1

decreases_activity of