General Information:

Id: 6,140 (click here to show other Interactions for entry)
Diseases: Colorectal cancer - [OMIM]
Diabetes mellitus, type II - [OMIM]
Insulin resistance
Homo sapiens
HCT116/L-OHP cells
article
Reference: Wang Z et al.Resveratrol induces AMPK-dependent MDR1 inhibition in colorectal cancer HCT116/L-OHP cells by preventing activation of NF-kappaB signaling and suppressing cAMP-responsive element transcriptional activity [PMID: 26124005]

Interaction Information:

Comment Resveratrol treatment also reduced nuclear factor-kappaB (NF-kappaB) activity, reduced phosphorylation levels of IkappaBalpha, and reduced nuclear translocation of the NF-kappaB subunit p65.
Formal Description
Interaction-ID: 57512

drug/chemical compound

Resveratrol

decreases_activity of

gene/protein

RELA

via decreased translocation into the nucleus
Drugbank entries Show/Hide entries for Resveratrol or RELA