General Information:

Id: 6,140 (click here to show other Interactions for entry)
Diseases: Colorectal cancer - [OMIM]
Diabetes mellitus, type II - [OMIM]
Insulin resistance
Homo sapiens
HCT116/L-OHP cells
Reference: Wang Z et al.Resveratrol induces AMPK-dependent MDR1 inhibition in colorectal cancer HCT116/L-OHP cells by preventing activation of NF-kappaB signaling and suppressing cAMP-responsive element transcriptional activity [PMID: 26124005]

Interaction Information:

Comment Resveratrol enhanced the intracellular accumulation of rhodamine 123, suggesting that resveratrol can reverse multi-drug resistance by downregulating MDR1 expression and reducing drug efflux.
Formal Description
Interaction-ID: 57508

drug/chemical compound


increases_quantity of

drug/chemical compound

Rhodamine 123

via decreased export
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