General Information:

Id: 613 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mammalia
article
Reference: Chen Y et al.(2009) Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimers amyloid peptides via up-regulating BACE1 transcription Proc. Natl. Acad. Sci. U.S.A. 106: 3907-3912 [PMID: 19237574]

Interaction Information:

Comment Metformin did not change the levels of full-length PS1 (presenilin 1, the core component of gamma-secretase) or its N-terminal fragment.
Formal Description
Interaction-ID: 3257

drug/chemical compound

Metformin

NOT affects_quantity of

gene/protein

PSEN1

Drugbank entries Show/Hide entries for Metformin