General Information:

Id: 6,130 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mus musculus
BTO:0002284 MIN-6 cell
Reference: Sato Y et al.(2014) Moderate hypoxia induces beta-cell dysfunction with HIF-1-independent gene expression changes PLoS ONE 9 [PMID: 25503986]

Interaction Information:

Comment Islet amyloid polypeptide (IAPP) aggregates into oligomers and forms fibrils in the islets, and the amyloid deposits are associated with reduced beta-cell mass in type 2 diabetic patients. An increased Iapp mRNA level was detected in the hypoxic MIN6 cells.
Formal Description
Interaction-ID: 57435

increases_expression of