General Information:

Id: 608 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Homo sapiens
BTO:0000007 HEK-293 cell
article
Reference: Kang DE et al.(1999) Presenilin 1 facilitates the constitutive turnover of beta-catenin: differential activity of Alzheimers disease-linked PS1 mutants in the beta-catenin-signaling pathway J. Neurosci. 19: 4229-4237 [PMID: 10341227]

Interaction Information:

Comment PS1 normally stimulates the degradation / turnover of beta-catenin.
Formal Description
Interaction-ID: 3246

gene/protein

PSEN1

decreases_quantity of

gene/protein

CTNNB1

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