General Information:

Id: 598 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Obesity - [OMIM]
Mus musculus
male
article
Reference: Cederroth CR et al.(2008) Dietary phytoestrogens activate AMP-activated protein kinase with improvement in lipid and glucose metabolism Diabetes 57: 1176-1185 [PMID: 18420492]

Interaction Information:

Comment The expression of genes essential for mitochondrial biogenesis and peroxisomal fatty acid oxidation, respectively peroxisome proliferator-activated receptor gamma co-activator 1 alpha (PGC-1 alpha) and peroxisome proliferator-activated receptor alpha (PPAR alpha), were upregulated in white adipose tissue, skeletal muscle, and liver of high-phytoestrogen-fed mice.
Formal Description
Interaction-ID: 3199

environment

high-phytoestrogen soy-based diet

increases_expression of

gene/protein

PPARGC1A