General Information:

Id: 595 (click here to show other Interactions for entry)
Diseases: Diabetes mellitus, type II - [OMIM]
Insulin resistance
Mammalia
article
Reference: Kim T et al.(2009) Curcumin activates AMPK and suppresses gluconeogenic gene expression in hepatoma cells. Biochem. Biophys. Res. Commun. 388: 377-382 [PMID: 19665995]

Interaction Information:

Comment Curcuminoids increased the phosphorylation of AMP-activated protein kinase (AMPK) and its downstream target acetyl-CoA carboxylase 2 (ACC2) in H4IIE and Hep3B cells with 400 times (curcumin) to 100,000 times (THC) the potency of metformin.
Formal Description
Interaction-ID: 3148

drug/chemical compound

Curcumin

increases_phosphorylation of

gene/protein

ACACB

in H4IIE and Hep3B cells
Drugbank entries Show/Hide entries for ACACB