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Field	Query

Alzheimer disease
Amyotrophic lateral sclerosis
Autism
Bipolar disorder
COXPD
Cancer
Cardiovascular diseases
Diabetes mellitus, type II
Epilepsy
Farber lipogranulomatosis
Inflammatory bowel disease
Lung disease
Major depressive disorder
Multiple sclerosis
Muscular atrophy
Neutropenia, severe congenital
Other
Parkinson disease
Post-traumatic stress disorder
Postpartum depression
Rare disease
Schizophrenia

	Field	Term

General Information:

Id:	5,909 (click here to show other Interactions for entry)
Diseases:	Osteoarthritis Sickle cell anemia - [OMIM]
Organism:	Homo sapiens
Tissue/Cell line:	endothelial cell line
Publication type:	article
Reference:	Li C et al.(2015) MicroRNA 648 Targets ET-1 mRNA and is cotranscriptionally regulated with MICAL3 by PAX5 Mol. Cell. Biol. 35: 514-528 [PMID: 25403488]

Interaction Information:

Comment	Hypoxia is a potent inducer of ET-1 gene expression in endothelial cells via activation of hypoxia-inducible factor 1alpha.
Formal Description Interaction-ID: 55794	process response to hypoxia increases_expression of gene/protein EDN1

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